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Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.
Xiao, Haopeng; Bozi, Luiz H M; Sun, Yizhi; Riley, Christopher L; Philip, Vivek M; Chen, Mandy; Li, Jiaming; Zhang, Tian; Mills, Evanna L; Emont, Margo P; Sun, Wenfei; Reddy, Anita; Garrity, Ryan; Long, Jiani; Becher, Tobias; Vitas, Laura Potano; Laznik-Bogoslavski, Dina; Ordonez, Martha; Liu, Xinyue; Chen, Xiong; Wang, Yun; Liu, Weihai; Tran, Nhien; Liu, Yitong; Zhang, Yang; Cypess, Aaron M; White, Andrew P; He, Yuchen; Deng, Rebecca; Schöder, Heiko; Paulo, Joao A; Jedrychowski, Mark P; Banks, Alexander S; Tseng, Yu-Hua; Cohen, Paul; Tsai, Linus T; Rosen, Evan D; Klein, Samuel; Chondronikola, Maria; McAllister, Fiona E; Van Bruggen, Nick; Huttlin, Edward L; Spiegelman, Bruce M; Churchill, Gary A; Gygi, Steven P; Chouchani, Edward T.
Afiliação
  • Xiao H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: haopeng_xiao@dfci.harvard.edu.
  • Bozi LHM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Sun Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Riley CL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Philip VM; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  • Chen M; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  • Li J; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Zhang T; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Mills EL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Emont MP; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Sun W; Department of Bioengineering, Stanford University, CA 94305, USA; Department of Molecular and Cellular Physiology, Stanford University, CA 94305, USA.
  • Reddy A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Garrity R; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Long J; College of Computing, Georgia Institute of Technology, Atlanta, GA 30332, USA.
  • Becher T; Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY 10065, USA.
  • Vitas LP; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Laznik-Bogoslavski D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Ordonez M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Liu X; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Chen X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Wang Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.
  • Liu W; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Tran N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Liu Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Zhang Y; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.
  • Cypess AM; Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • White AP; Department of Orthopedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • He Y; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Deng R; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Schöder H; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Jedrychowski MP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Banks AS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Tseng YH; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.
  • Cohen P; Laboratory of Molecular Metabolism, The Rockefeller University, New York, NY 10065, USA.
  • Tsai LT; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Rosen ED; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Klein S; Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chondronikola M; Department of Nutrition, UC Davis, Davis, CA 95616, USA.
  • McAllister FE; Calico Life Sciences LLC, South San Francisco, CA 94080, USA.
  • Van Bruggen N; Calico Life Sciences LLC, South San Francisco, CA 94080, USA.
  • Huttlin EL; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Spiegelman BM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Churchill GA; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  • Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Chouchani ET; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: edwardt_chouchani@dfci.harvard.edu.
Cell ; 185(24): 4654-4673.e28, 2022 11 23.
Article em En | MEDLINE | ID: mdl-36334589
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo Marrom / Proteoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo Marrom / Proteoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article