NCCN Guidelines® Insights: Gastrointestinal Stromal Tumors, Version 2.2022.
J Natl Compr Canc Netw
; 20(11): 1204-1214, 2022 11.
Article
em En
| MEDLINE
| ID: mdl-36351335
ABSTRACT
Gastrointestinal stromal tumors (GIST) are the most common type of soft tissue sarcoma that occur throughout the gastrointestinal tract. Most of these tumors are caused by oncogenic activating mutations in the KIT or PDGFRA genes. The NCCN Guidelines for GIST provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with these tumors. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines, including revised systemic therapy options for unresectable, progressive, or metastatic GIST based on mutational status, and updated recommendations for the management of GIST that develop resistance to specific tyrosine kinase inhibitors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tumores do Estroma Gastrointestinal
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Qualitative_research
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article