Role of PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway in Resveratrol Alleviation of Zearalenone-Induced Oxidative Stress and Apoptosis in TM4 Cells.

Xu, Wenlin; Zheng, Hao; Fu, Youtian; Gu, Yayi; Zou, Hui; Yuan, Yan; Gu, Jianhong; Liu, Zongping; Bian, Jianchun

Xu, Wenlin; Zheng, Hao; Fu, Youtian; Gu, Yayi; Zou, Hui; Yuan, Yan; Gu, Jianhong; Liu, Zongping; Bian, Jianchun.

Afiliação

Xu W; College of Veterinary Medicine, Yangzhou University, 12 Wenhui East Road, Yangzhou 225009, China.
Zheng H; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.
Fu Y; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Gu Y; College of Veterinary Medicine, Yangzhou University, 12 Wenhui East Road, Yangzhou 225009, China.
Zou H; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.
Yuan Y; College of Veterinary Medicine, Yangzhou University, 12 Wenhui East Road, Yangzhou 225009, China.
Gu J; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.
Liu Z; College of Veterinary Medicine, Yangzhou University, 12 Wenhui East Road, Yangzhou 225009, China.
Bian J; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.

Toxins (Basel) ; 14(11)2022 10 26.

Article em En | MEDLINE | ID: mdl-36355983

Assuntos

Fator 2 Relacionado a NF-E2; Zearalenona; Animais; Masculino; Fator 2 Relacionado a NF-E2/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Heme Oxigenase-1/metabolismo; Fosfatidilinositol 3-Quinase/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Resveratrol/farmacologia; Zearalenona/metabolismo; Espécies Reativas de Oxigênio/metabolismo; RNA Interferente Pequeno; Estresse Oxidativo; Transdução de Sinais; Apoptose; Antioxidantes/farmacologia

Palavras-chave

Nrf2/HO-1 signaling pathway; PI3K/Akt signaling pathway; ROS; TM4 cells; cytotoxicity; oxidative damage; resveratrol; zearalenone

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zearalenona / Fator 2 Relacionado a NF-E2 Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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