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Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial.
Schlaich, Markus P; Bellet, Marc; Weber, Michael A; Danaietash, Parisa; Bakris, George L; Flack, John M; Dreier, Roland F; Sassi-Sayadi, Mouna; Haskell, Lloyd P; Narkiewicz, Krzysztof; Wang, Ji-Guang.
Afiliação
  • Schlaich MP; Dobney Hypertension Centre, Royal Perth Hospital Research Foundation, Medical School, The University of Western Australia, Perth, WA, Australia; Department of Cardiology and Department of Nephrology, Royal Perth Hospital, Perth, WA, Australia. Electronic address: markus.schlaich@uwa.edu.au.
  • Bellet M; Global Clinical Development, Idorsia Pharmaceuticals, Allschwil, Switzerland.
  • Weber MA; Downstate College of Medicine, State University of New York, Brooklyn, NY, USA.
  • Danaietash P; Global Clinical Development, Idorsia Pharmaceuticals, Allschwil, Switzerland.
  • Bakris GL; Department of Medicine, American Heart Association Comprehensive Hypertension Center, The University of Chicago Medicine, Chicago, IL, USA.
  • Flack JM; Division of General Internal Medicine, Hypertension Section, Department of Medicine, Hypertension Section, Southern Illinois University School of Medicine, Springfield, IL, USA.
  • Dreier RF; Global Clinical Development, Idorsia Pharmaceuticals, Allschwil, Switzerland.
  • Sassi-Sayadi M; Department of Biometry, Idorsia Pharmaceuticals, Allschwil, Switzerland.
  • Haskell LP; The Janssen Pharmaceutical Companies of Johnson & Johnson, Raritan, NJ, USA.
  • Narkiewicz K; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland.
  • Wang JG; Department of Hypertension, The Shanghai Institute of Hypertension, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lancet ; 400(10367): 1927-1937, 2022 12 03.
Article em En | MEDLINE | ID: mdl-36356632
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antagonistas dos Receptores de Endotelina / Hipertensão / Anti-Hipertensivos Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antagonistas dos Receptores de Endotelina / Hipertensão / Anti-Hipertensivos Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article