Ginsenoside Compound K Ameliorates Development of Diabetic Kidney Disease through Inhibiting TLR4 Activation Induced by Microbially Produced Imidazole Propionate.

Chen, Qian; Ren, Dongwen; Liu, Luokun; Xu, Jingge; Wu, Yuzheng; Yu, Haiyang; Liu, Mengyang; Zhang, Yi; Wang, Tao

Chen, Qian; Ren, Dongwen; Liu, Luokun; Xu, Jingge; Wu, Yuzheng; Yu, Haiyang; Liu, Mengyang; Zhang, Yi; Wang, Tao.

Afiliação

Chen Q; State Key Laboratory of Component Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Ren D; Haihe Laboratory of Modern Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Liu L; State Key Laboratory of Component Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Xu J; Haihe Laboratory of Modern Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Wu Y; Haihe Laboratory of Modern Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Yu H; State Key Laboratory of Component Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Liu M; Haihe Laboratory of Modern Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Zhang Y; Haihe Laboratory of Modern Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.
Wang T; State Key Laboratory of Component Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin 301617, China.

Int J Mol Sci ; 23(21)2022 Oct 25.

Article em En | MEDLINE | ID: mdl-36361652

Assuntos

Diabetes Mellitus; Nefropatias Diabéticas; Animais; Camundongos; Diabetes Mellitus/metabolismo; Nefropatias Diabéticas/metabolismo; Rim/metabolismo; Receptor 4 Toll-Like/metabolismo

Palavras-chave

TLR4; diabetic kidney disease; ginsenoside compound K; gut microbiota; imidazole propionate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Nefropatias Diabéticas Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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