7-Hydroxycoumarin Induces Vasorelaxation in Animals with Essential Hypertension: Focus on Potassium Channels and Intracellular Ca<sup>2+</sup> Mobilization.

Jesus, Rafael L C; Silva, Isnar L P; Araújo, Fênix A; Moraes, Raiana A; Silva, Liliane B; Brito, Daniele S; Lima, Gabriela B C; Alves, Quiara L; Silva, Darizy F

7-Hydroxycoumarin Induces Vasorelaxation in Animals with Essential Hypertension: Focus on Potassium Channels and Intracellular Ca²⁺ Mobilization.

Jesus, Rafael L C; Silva, Isnar L P; Araújo, Fênix A; Moraes, Raiana A; Silva, Liliane B; Brito, Daniele S; Lima, Gabriela B C; Alves, Quiara L; Silva, Darizy F.

Afiliação

Jesus RLC; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Silva ILP; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Araújo FA; Gonçalo Moniz Institute, Oswaldo Cruz Foundation-FIOCRUZ, Salvador 40296-710, Brazil.
Moraes RA; Gonçalo Moniz Institute, Oswaldo Cruz Foundation-FIOCRUZ, Salvador 40296-710, Brazil.
Silva LB; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Brito DS; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Lima GBC; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Alves QL; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.
Silva DF; Laboratory of Cardiovascular Physiology and Pharmacology, Federal University of Bahia, Salvador 40110-902, Brazil.

Molecules ; 27(21)2022 Oct 28.

Article em En | MEDLINE | ID: mdl-36364149

Assuntos

Hipertensão; Vasodilatação; Ratos; Animais; Canais de Potássio/metabolismo; Hipertensão Essencial; Ratos Endogâmicos SHR; Vasodilatadores/farmacologia; Endotélio Vascular/metabolismo; Anti-Hipertensivos/farmacologia; Umbeliferonas/farmacologia

Palavras-chave

7-hydroxycoumarin; hypertensive rats; isometric records; superior mesenteric artery superior; umbelliferone; vasorelaxation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vasodilatação / Hipertensão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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