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Evaluation of 11 commercially available PCR kits for the detection of monkeypox virus DNA, Berlin, July to September 2022.
Michel, Janine; Targosz, Angelina; Rinner, Thomas; Bourquain, Daniel; Brinkmann, Annika; Sacks, Jilian Amber; Schaade, Lars; Nitsche, Andreas.
Afiliação
  • Michel J; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Targosz A; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Rinner T; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Bourquain D; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Brinkmann A; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Sacks JA; World Health Organization (WHO), Department of Epidemic and Pandemic Preparedness and Prevention, Geneva, Switzerland.
  • Schaade L; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
  • Nitsche A; Robert Koch Institute (RKI), Center for Biological Threats and Special Pathogens, German Reference Laboratory for Poxviruses, Berlin, Germany.
Euro Surveill ; 27(45)2022 11.
Article em En | MEDLINE | ID: mdl-36367010
ABSTRACT
Before the international spread of monkeypox in May 2022, PCR kits for the detection of orthopoxviruses, and specifically monkeypox virus, were rarely available. Here we describe the evaluation of 11 recently developed commercially available PCR kits for the detection of monkeypox virus DNA. All tested kits are currently intended for research use only and clinical performance still needs to be assessed in more detail, but all were suitable for diagnostics of monkeypox virus, with variations in specificity rather than sensitivity.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mpox Tipo de estudo: Diagnostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mpox Tipo de estudo: Diagnostic_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article