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Hemodynamic response to intestinal pH stimulation measured with spectroscopic video imaging.
Funane, Tsukasa; Yokoi, Yuki; Kiguchi, Masashi; Shinozaki, Ryuga; Ayabe, Tokiyoshi; Atsumori, Hirokazu; Nishimura, Ayako; Nakamura, Kiminori; Kandori, Akihiko.
Afiliação
  • Funane T; Center for Exploratory Research, Research & Development Group, Hitachi. Ltd, Kokubunji, Tokyo 185-8601, Japan.
  • Yokoi Y; Faculty of Advanced Life Science, Hokkaido University, N10, W8, Kita-ku, Sapporo 060-0810, Japan.
  • Kiguchi M; Center for Exploratory Research, Research & Development Group, Hitachi. Ltd, Kokubunji, Tokyo 185-8601, Japan.
  • Shinozaki R; Faculty of Advanced Life Science, Hokkaido University, N10, W8, Kita-ku, Sapporo 060-0810, Japan.
  • Ayabe T; Faculty of Advanced Life Science, Hokkaido University, N10, W8, Kita-ku, Sapporo 060-0810, Japan.
  • Atsumori H; Center for Exploratory Research, Research & Development Group, Hitachi. Ltd, Kokubunji, Tokyo 185-8601, Japan.
  • Nishimura A; Center for Exploratory Research, Research & Development Group, Hitachi. Ltd, Kokubunji, Tokyo 185-8601, Japan.
  • Nakamura K; Faculty of Advanced Life Science, Hokkaido University, N10, W8, Kita-ku, Sapporo 060-0810, Japan.
  • Kandori A; Center for Exploratory Research, Research & Development Group, Hitachi. Ltd, Kokubunji, Tokyo 185-8601, Japan.
Biomed Phys Eng Express ; 9(1)2022 11 23.
Article em En | MEDLINE | ID: mdl-36368027
To investigate the relationship between the gut and skin (gut-skin axis), head skin hemodynamic responses to gut stimulation including the injection of acetic acid in nude mice were measured by spectroscopic video imaging, which was calculated using a modified Beer-Lambert formula. The relationship with blood proteins was also analyzed. The blood volume changes in three mice injected with acetic acid were highly reproducible in the mathematical model equation. Four proteins correlated with blood volume changes were all related to immunity. These results suggest that intestinal pH can alter the blood volume in the skin and induce immune-related responses.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Hemodinâmica Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Hemodinâmica Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article