TreeQNet: a webserver for Treatment evaluation with Quantified Network.

BACKGROUND: Personalized therapy has been at the forefront of cancer care, making cancer treatment more effective. Since cancer patients respond individually to drug therapy, predicting the sensitivity of each patient to specific drugs is very helpful to apply therapeutic agents. Traditional methods focus on node (molecular) information but ignore relevant interactions among different nodes, which has very limited application in complex situations, such as cancer drug responses in real clinical practice. RESULTS: Treatment evaluation with Quantified Network (TreeQNet) is a webserver which could predict sensitivity to drugs for patients through the innovative use of proteomic and phosphoproteomic network from tumor tissues. CONCLUSION: TreeQNet service: http://bioinfo.ustc.edu.cn/ . TreeQNet source code: https://github.com/Really00/treeqnet-web-front/ .