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Verbal memory following weight gain in adult patients with anorexia nervosa: A longitudinal study.
Terhoeven, Valentin; Faschingbauer, Sandra; Huber, Julia; Herzog, Wolfgang; Friederich, Hans-Christoph; Simon, Joe J; Nikendei, Christoph.
Afiliação
  • Terhoeven V; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
  • Faschingbauer S; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
  • Huber J; Institute of Medical Psychology, Center for Psychosocial Medicine, Heidelberg University, Heidelberg, Germany.
  • Herzog W; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
  • Friederich HC; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
  • Simon JJ; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
  • Nikendei C; Department for General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Heidelberg, Germany.
Eur Eat Disord Rev ; 31(2): 271-284, 2023 03.
Article em En | MEDLINE | ID: mdl-36397677
BACKGROUND: Patients with Anorexia Nervosa (AN) show a moderate deficit in overall neuropsychological functioning. Since previous studies on memory performance mainly employed cross-sectional designs, the present study aims to investigate changes in verbal memory following weight-gain. METHODS: Verbal memory was assessed with the Wechsler Memory Scale-Revised (WMS-R; 'logical memory'-story-recall-subtest) and the California Verbal Learning Test-II (CVLT-II; 'verbal learning'). Included were 31 female patients with AN (18 restricting-, 13 purging-subtype; average disease duration: 5.1 years; average baseline BMI: 14.4 kg/m2 ) and 24 medication-free normal-weight healthy women adjusted for age at baseline (T0). In a post-treatment assessment of approx. 6 weeks with weight increase (T1), 18 patients with AN and 20 healthy women were assessed again. Group differences in verbal memory (i.e., WMS-R, CVLT-II) were assessed for the baseline comparisons with a multivariate ANOVA and longitudinal data were analysed with repeated measures (RM) ANOVAs. RESULTS: At baseline, patients with AN as compared to healthy women displayed deficits in logical memory. In the follow-up assessment, patients with AN improved their logical memory significantly compared to healthy controls (p < 0.006). Furthermore, groups did not differ in verbal learning neither before nor after inpatient treatment. CONCLUSIONS: Enhanced logical memory in patients with AN following weight-gain is probably due to the impaired memory as compared to healthy controls at T0. A survivorship bias could explain the improved memory performance in longitudinal data in contrast to cross-sectional studies. Patients with AN with poorer memory performance before inpatient treatment are at higher risk to drop out and need support.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rememoração Mental / Anorexia Nervosa Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rememoração Mental / Anorexia Nervosa Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article