Beta-blockers and mechanical dyssynchrony in heart failure assessed by radionuclide ventriculography.
J Nucl Cardiol
; 30(1): 193-200, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-36417121
ABSTRACT
BACKGROUND:
Radionuclide ventriculography (RNVG) can be used to quantify mechanical dyssynchrony and may be a valuable adjunct in the assessment of heart failure with reduced ejection fraction (HFrEF). The study aims to investigate the effect of beta-blockers on mechanical dyssynchrony using novel RNVG phase parameters.METHODS:
A retrospective study was carried out in a group of 98 patients with HFrEF. LVEF and dyssynchrony were assessed pre and post beta-blockade. Dyssynchrony was assessed using synchrony, entropy, phase standard deviation, approximate entropy, and sample entropy from planar RNVG phase images. Subgroups split by ischemic etiology were also investigated.RESULTS:
An improvement in dyssynchrony and LVEF was measured six months post beta-blockade for both ischemic and non-ischemic groups.CONCLUSIONS:
A significant improvement in dyssynchrony and LVEF was measured post beta-blockade using novel measures of dyssynchrony.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Disfunção Ventricular Esquerda
/
Insuficiência Cardíaca
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article