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Deep mutational scan of a drug efflux pump reveals its structure-function landscape.
Meier, Gianmarco; Thavarasah, Sujani; Ehrenbolger, Kai; Hutter, Cedric A J; Hürlimann, Lea M; Barandun, Jonas; Seeger, Markus A.
Afiliação
  • Meier G; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
  • Thavarasah S; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
  • Ehrenbolger K; Laboratory for Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
  • Hutter CAJ; Science for Life Laboratory, Umeå University, Umeå, Sweden.
  • Hürlimann LM; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
  • Barandun J; Linkster Therapeutics AG, Zurich, Switzerland.
  • Seeger MA; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
Nat Chem Biol ; 19(4): 440-450, 2023 04.
Article em En | MEDLINE | ID: mdl-36443574

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Transportadores de Cassetes de Ligação de ATP Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Transportadores de Cassetes de Ligação de ATP Idioma: En Ano de publicação: 2023 Tipo de documento: Article