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PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment.
Missiroli, Sonia; Perrone, Mariasole; Gafà, Roberta; Nicoli, Francesco; Bonora, Massimo; Morciano, Giampaolo; Boncompagni, Caterina; Marchi, Saverio; Lebiedzinska-Arciszewska, Magdalena; Vezzani, Bianca; Lanza, Giovanni; Kricek, Franz; Borghi, Alessandro; Fiorica, Francesco; Ito, Keisuke; Wieckowski, Mariusz R; Di Virgilio, Francesco; Abelli, Luigi; Pinton, Paolo; Giorgi, Carlotta.
Afiliação
  • Missiroli S; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Perrone M; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Gafà R; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
  • Nicoli F; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy.
  • Bonora M; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Morciano G; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Boncompagni C; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Marchi S; Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
  • Lebiedzinska-Arciszewska M; Laboratory of Mitochondrial Biology and Metabolism, Nencki Institute of Experimental Biology, Warsaw, Poland.
  • Vezzani B; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Lanza G; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
  • Kricek F; NBS-C Bioscience & Consulting GmbH, Vienna, Austria.
  • Borghi A; Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University Hospital of Ferrara, Ferrara, Italy.
  • Fiorica F; Department of Radiation Oncology and Nuclear Medicine, AULSS 9 Scaligera, Verona, Italy.
  • Ito K; Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Departments of Cell Biology and Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Wieckowski MR; Laboratory of Mitochondrial Biology and Metabolism, Nencki Institute of Experimental Biology, Warsaw, Poland.
  • Di Virgilio F; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Abelli L; Department of Life Sciences and Biotechnology, Section of Biology and Evolution, University of Ferrara, Ferrara, Italy.
  • Pinton P; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Giorgi C; Department of Medical Sciences, Section of Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy. carlotta.giorgi@unife.it.
Cell Death Differ ; 30(2): 429-441, 2023 02.
Article em En | MEDLINE | ID: mdl-36450825
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Purinérgicos P2X7 / Microambiente Tumoral / Proteína 3 que Contém Domínio de Pirina da Família NLR / Proteína da Leucemia Promielocítica Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Purinérgicos P2X7 / Microambiente Tumoral / Proteína 3 que Contém Domínio de Pirina da Família NLR / Proteína da Leucemia Promielocítica Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article