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A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE.
Watts, Jason A; Grunseich, Christopher; Rodriguez, Yesenia; Liu, Yaojuan; Li, Dongjun; Burdick, Joshua T; Bruzel, Alan; Crouch, Robert J; Mahley, Robert W; Wilson, Samuel H; Cheung, Vivian G.
Afiliação
  • Watts JA; Department of Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  • Grunseich C; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.
  • Rodriguez Y; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  • Liu Y; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.
  • Li D; Department of Pediatrics and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Burdick JT; Department of Pediatrics and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Bruzel A; Department of Pediatrics and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Crouch RJ; Department of Pediatrics and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Mahley RW; Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Wilson SH; Gladstone Institute of Neurological Disease, San Francisco, CA, USA.
  • Cheung VG; Departments of Pathology and Medicine, University of California, San Francisco, CA, USA.
Nucleic Acids Res ; 50(21): 12497-12514, 2022 11 28.
Article em En | MEDLINE | ID: mdl-36453989

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Estruturas R-Loop Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Estruturas R-Loop Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article