Rapid detection of &#945;-amanitin and ß-amanitin in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to the toxicokinetic study of Lepiota brunneoincarnata.

Mao, Zhengsheng; Yu, Youjia; Sun, Hao; Cao, Yue; Jiang, Qiaoyan; Chu, Chunyan; Sun, Yang; Huang, Shuainan; Zhang, Jinsong; Chen, Feng

Rapid detection of α-amanitin and ß-amanitin in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to the toxicokinetic study of Lepiota brunneoincarnata.

Mao, Zhengsheng; Yu, Youjia; Sun, Hao; Cao, Yue; Jiang, Qiaoyan; Chu, Chunyan; Sun, Yang; Huang, Shuainan; Zhang, Jinsong; Chen, Feng.

Afiliação

Mao Z; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China. maozhengsheng@njmu.edu.cn.
Yu Y; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Sun H; Department of Emergency, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Cao Y; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Jiang Q; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Chu C; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Sun Y; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Huang S; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Zhang J; Department of Emergency, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China. zhangjso@njmu.edu.cn.
Chen F; Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China. fchen@njmu.edu.cn.

Forensic Toxicol ; 40(1): 111-118, 2022 01.

Article em En | MEDLINE | ID: mdl-36454499

Assuntos

Agaricales; Alfa-Amanitina; Ratos; Animais; Alfa-Amanitina/toxicidade; Cromatografia Líquida; Toxicocinética; Espectrometria de Massas em Tandem

Palavras-chave

Lepiota brunneoincarnata; Toxicokinetics; UPLC−MS/MS; α-Amanitin; ß-Amanitin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agaricales / Alfa-Amanitina Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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