Progressive multifocal leukoencephalopathy in multiple myeloma.
Eur J Haematol
; 110(3): 322-329, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36465014
ABSTRACT
Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal demyelinating disease of the central nervous system caused by reactivation of the JC virus in the context of immune suppression such as HIV, malignancy, and certain immunomodulatory medications. PML has been reported only rarely in multiple myeloma patients, and its presenting features and natural history in this population are not well known. We describe six cases of PML among multiple myeloma patients treated at our institution between 2013 and 2022, including two that developed on or shortly after treatment with recently developed BCMA-directed immunotherapies.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Leucoencefalopatia Multifocal Progressiva
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Vírus JC
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Mieloma Múltiplo
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article