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Heterogeneous graph construction and HinSAGE learning from electronic medical records.
Cho, Ha Na; Ahn, Imjin; Gwon, Hansle; Kang, Hee Jun; Kim, Yunha; Seo, Hyeram; Choi, Heejung; Kim, Minkyoung; Han, Jiye; Kee, Gaeun; Jun, Tae Joon; Kim, Young-Hak.
Afiliação
  • Cho HN; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Ahn I; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Gwon H; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Kang HJ; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Kim Y; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Seo H; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Choi H; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Kim M; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Han J; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Kee G; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Jun TJ; Big Data Research Center, Asan Institute for Life Sciences, Asan Medical Center, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea.
  • Kim YH; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Songpagu, 05505, Seoul, Republic of Korea. mdyhkim@amc.seoul.kr.
Sci Rep ; 12(1): 21152, 2022 12 07.
Article em En | MEDLINE | ID: mdl-36477457
ABSTRACT
Graph representation learning is a method for introducing how to effectively construct and learn patient embeddings using electronic medical records. Adapting the integration will support and advance the previous methods to predict the prognosis of patients in network models. This study aims to address the challenge of implementing a complex and highly heterogeneous dataset, including the following (1) demonstrating how to build a multi-attributed and multi-relational graph model (2) and applying a downstream disease prediction task of a patient's prognosis using the HinSAGE algorithm. We present a bipartite graph schema and a graph database construction in detail. The first constructed graph database illustrates a query of a predictive network that provides analytical insights using a graph representation of a patient's journey. Moreover, we demonstrate an alternative bipartite model where we apply the model to the HinSAGE to perform the link prediction task for predicting the event occurrence. Consequently, the performance evaluation indicated that our heterogeneous graph model was successfully predicted as a baseline model. Overall, our graph database successfully demonstrated efficient real-time query performance and showed HinSAGE implementation to predict cardiovascular disease event outcomes on supervised link prediction learning.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Registros Eletrônicos de Saúde Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Registros Eletrônicos de Saúde Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article