Recent advances in ATM inhibitors as potential therapeutic agents.

Dong, Chao; Wang, Yong; Tu, Zhenlin; Yan, Jingxue; Jiang, Yiqing; Lu, Tao; Chen, Yadong; Liu, Haichun

Dong, Chao; Wang, Yong; Tu, Zhenlin; Yan, Jingxue; Jiang, Yiqing; Lu, Tao; Chen, Yadong; Liu, Haichun.

Afiliação

Dong C; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Wang Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Tu Z; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Yan J; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Jiang Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Lu T; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.
Chen Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China.
Liu H; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, PR China.

Future Med Chem ; 14(23): 1811-1830, 2022 12.

Article em En | MEDLINE | ID: mdl-36484176

Assuntos

Proteínas de Ciclo Celular; Proteínas Serina-Treonina Quinases; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo; Proteínas de Ligação a DNA; Proteínas Mutadas de Ataxia Telangiectasia/genética; Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Dano ao DNA

Palavras-chave

ATM; ATM inhibitors; DNA damage response; structureactivity relationship

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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