How we approach transfusions in a patient with high risk of alloimmunization from McLeod phenotype.
Pediatr Blood Cancer
; 70(2): e30119, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-36495235
ABSTRACT
McLeod phenotype-caused by the missing Xk protein-is a very rare red cell phenotype, one characteristic of McLeod syndrome, and sometimes associated with X-linked chronic granulomatous disease (CGD). Diagnosis of McLeod phenotype is important for appropriate transfusion management, because red blood cells from all healthy donors will have the Xk protein with its Kx antigen and can lead to red cell antibody formation without the ability to find compatible McLeod phenotype blood for transfusion. We offer a review and approach to diagnosis of the McLeod phenotype and special transfusion considerations.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neuroacantocitose
/
Doença Granulomatosa Crônica
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article