A Study to Evaluate Relative Bioavailability, Food Effect, and Pharmacodynamics of Tropifexor, a Farnesoid X Receptor Agonist, in Healthy Participants.

Stringer, Rowan; Chen, Jin; Shah, Bharti; Gu, Jessie; Zhang, Yiming; Prince, William; Klickstein, Lloyd B; Woessner, Ralph

Stringer, Rowan; Chen, Jin; Shah, Bharti; Gu, Jessie; Zhang, Yiming; Prince, William; Klickstein, Lloyd B; Woessner, Ralph.

Afiliação

Stringer R; Novartis Institutes for BioMedical Research, PK Sciences, Basel, Switzerland.
Chen J; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Shah B; Novartis Institutes for Biomedical Research, East Hanover, New Jersey, USA.
Gu J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Zhang Y; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Prince W; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Klickstein LB; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Woessner R; Novartis Institutes for BioMedical Research, PK Sciences, Basel, Switzerland.

Clin Pharmacol Drug Dev ; 12(2): 122-131, 2023 02.

Article em En | MEDLINE | ID: mdl-36495282

Assuntos

Interações Alimento-Droga; Humanos; Área Sob a Curva; Disponibilidade Biológica; Estudos Cross-Over; Voluntários Saudáveis

Palavras-chave

bioavailability; pharmacodynamics; pharmacokinetics; prototype final market image

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interações Alimento-Droga Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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