A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy.

Bordoloi, Devivasha; Bhojnagarwala, Pratik S; Perales-Puchalt, Alfredo; Kulkarni, Abhijeet J; Zhu, Xizhou; Liaw, Kevin; O'Connell, Ryan P; Park, Daniel H; Kulp, Daniel W; Zhang, Rugang; Weiner, David B

Bordoloi, Devivasha; Bhojnagarwala, Pratik S; Perales-Puchalt, Alfredo; Kulkarni, Abhijeet J; Zhu, Xizhou; Liaw, Kevin; O'Connell, Ryan P; Park, Daniel H; Kulp, Daniel W; Zhang, Rugang; Weiner, David B.

Afiliação

Bordoloi D; Vaccine & Immunotherapy Center and.
Bhojnagarwala PS; Vaccine & Immunotherapy Center and.
Perales-Puchalt A; Vaccine & Immunotherapy Center and.
Kulkarni AJ; Vaccine & Immunotherapy Center and.
Zhu X; Vaccine & Immunotherapy Center and.
Liaw K; Vaccine & Immunotherapy Center and.
O'Connell RP; Vaccine & Immunotherapy Center and.
Park DH; Vaccine & Immunotherapy Center and.
Kulp DW; Vaccine & Immunotherapy Center and.
Zhang R; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania, USA.
Weiner DB; Vaccine & Immunotherapy Center and.

JCI Insight ; 7(22)2022 11 22.

Article em En | MEDLINE | ID: mdl-36509287

Assuntos

Neoplasias Ovarianas; Receptores do FSH; Humanos; Animais; Camundongos; Feminino; Receptores do FSH/genética; Receptores do FSH/metabolismo; Recidiva Local de Neoplasia; Imunoterapia; Neoplasias Ovarianas/genética; Neoplasias Ovarianas/terapia; Neoplasias Ovarianas/patologia; Anticorpos Monoclonais/uso terapêutico; Imunidade Adaptativa; Microambiente Tumoral

Palavras-chave

Adaptive immunity; Cancer; Immunotherapy; Oncology; Therapeutics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Receptores do FSH Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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