A feedback loop between NONHSAT024276 and PTBP1 inhibits tumor progression and glycolysis in HCC by increasing the PKM1/PKM2 ratio.

Li, Yuwei; Chen, Xia; Huang, Hengliu; Liao, Ling; Chong, Huimin; Li, Guangyao; Yuan, Tao; Lu, Weiping; Deng, Shaoli; Huang, Qing

Li, Yuwei; Chen, Xia; Huang, Hengliu; Liao, Ling; Chong, Huimin; Li, Guangyao; Yuan, Tao; Lu, Weiping; Deng, Shaoli; Huang, Qing.

Afiliação

Li Y; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Chen X; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Huang H; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Liao L; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Chong H; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Li G; Department of Hepatobiliary Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Yuan T; Department of Hepatobiliary Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Lu W; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Deng S; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Huang Q; Department of Laboratory Medicine, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, China.

Cancer Sci ; 114(4): 1519-1540, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36529521

Assuntos

Carcinoma Hepatocelular; Ribonucleoproteínas Nucleares Heterogêneas; Neoplasias Hepáticas; Proteína de Ligação a Regiões Ricas em Polipirimidinas; RNA Longo não Codificante; Humanos; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Linhagem Celular Tumoral; Proliferação de Células/genética; Retroalimentação; Glicólise/genética; Ribonucleoproteínas Nucleares Heterogêneas/genética; Ribonucleoproteínas Nucleares Heterogêneas/metabolismo; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Proteína de Ligação a Regiões Ricas em Polipirimidinas/genética; Proteína de Ligação a Regiões Ricas em Polipirimidinas/metabolismo; Piruvato Quinase/genética; RNA Longo não Codificante/genética

Palavras-chave

PTBP1; glycolysis; hepatocellular carcinoma; lncRNA; pyruvate kinase

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Proteína de Ligação a Regiões Ricas em Polipirimidinas / Ribonucleoproteínas Nucleares Heterogêneas / RNA Longo não Codificante / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google