The 2019-2020 Dengue Fever Epidemic: Genomic Markers Indicating Severity in Dominican Republic Children.
J Pediatric Infect Dis Soc
; 12(3): 169-172, 2023 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-36537278
ABSTRACT
We performed an observational cohort study to assess associations between genetic factors of dengue fever (DF) severity in children in the Dominican Republic. A total of 488 participants had serologically confirmed DF. We replicated the association between the IFIH1 gene (rs1990760) and severe DF (n = 80/488, p = 0.006) and identified novel associations needing further investigation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dengue Grave
/
Dengue
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child
/
Humans
País como assunto:
Caribe ingles
/
Dominica
/
Republica dominicana
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article