Meningeal lymphatic drainage promotes T cell responses against <i>Toxoplasma gondii</i> but is dispensable for parasite control in the brain.

Kovacs, Michael A; Cowan, Maureen N; Babcock, Isaac W; Sibley, Lydia A; Still, Katherine; Batista, Samantha J; Labuzan, Sydney A; Sethi, Ish; Harris, Tajie H

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.

Kovacs, Michael A; Cowan, Maureen N; Babcock, Isaac W; Sibley, Lydia A; Still, Katherine; Batista, Samantha J; Labuzan, Sydney A; Sethi, Ish; Harris, Tajie H.

Afiliação

Kovacs MA; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Cowan MN; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Babcock IW; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Sibley LA; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Still K; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Batista SJ; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Labuzan SA; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Sethi I; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.
Harris TH; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, United States.

Elife ; 112022 12 21.

Article em En | MEDLINE | ID: mdl-36541708

Assuntos

Toxoplasma; Camundongos; Animais; Encéfalo/metabolismo; Meninges/patologia; Linfócitos T CD8-Positivos; Controle de Doenças Transmissíveis

Palavras-chave

T cells; Toxoplasma gondii; immunology; infectious disease; inflammation; lymphatics; microbiology; neuroimmunology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article