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Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation.
Biggs, Catherine M; Cordeiro-Santanach, Anna; Prykhozhij, Sergey V; Deveau, Adam P; Lin, Yi; Del Bel, Kate L; Orben, Felix; Ragotte, Robert J; Saferali, Aabida; Mostafavi, Sara; Dinh, Louie; Dai, Darlene; Weinacht, Katja G; Dobbs, Kerry; Ott de Bruin, Lisa; Sharma, Mehul; Tsai, Kevin; Priatel, John J; Schreiber, Richard A; Rozmus, Jacob; Hosking, Martin Ck; Shopsowitz, Kevin E; McKinnon, Margaret L; Vercauteren, Suzanne; Seear, Michael; Notarangelo, Luigi D; Lynn, Francis C; Berman, Jason N; Turvey, Stuart E.
Afiliação
  • Biggs CM; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Cordeiro-Santanach A; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Prykhozhij SV; AGADA Biosciences Inc., Halifax, Nova Scotia, Canada.
  • Deveau AP; CHEO Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
  • Lin Y; Department of Internal Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
  • Del Bel KL; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Orben F; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Ragotte RJ; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Saferali A; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Mostafavi S; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Dinh L; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Dai D; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Weinacht KG; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Dobbs K; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Ott de Bruin L; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Sharma M; Department of Medical Genetics and.
  • Tsai K; Department of Statistics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Priatel JJ; Department of Medical Genetics and.
  • Schreiber RA; Department of Statistics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Rozmus J; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Hosking MC; Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford School of Medicine, Stanford, California, USA.
  • Shopsowitz KE; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
  • McKinnon ML; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Vercauteren S; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Seear M; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Notarangelo LD; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Lynn FC; Department of Pathology and Laboratory Medicine and.
  • Berman JN; BC Children's Hospital, Vancouver, British Columbia, Canada.
  • Turvey SE; Department of Pathology and Laboratory Medicine and.
JCI Insight ; 7(24)2022 12 22.
Article em En | MEDLINE | ID: mdl-36546480
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eosinofilia / Células-Tronco Pluripotentes Induzidas / Hipersensibilidade / Hipersensibilidade Imediata Tipo de estudo: Etiology_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eosinofilia / Células-Tronco Pluripotentes Induzidas / Hipersensibilidade / Hipersensibilidade Imediata Tipo de estudo: Etiology_studies Limite: Animals / Child / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article