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The sound of silence: Transgene silencing in mammalian cell engineering.
Cabrera, Alan; Edelstein, Hailey I; Glykofrydis, Fokion; Love, Kasey S; Palacios, Sebastian; Tycko, Josh; Zhang, Meng; Lensch, Sarah; Shields, Cara E; Livingston, Mark; Weiss, Ron; Zhao, Huimin; Haynes, Karmella A; Morsut, Leonardo; Chen, Yvonne Y; Khalil, Ahmad S; Wong, Wilson W; Collins, James J; Rosser, Susan J; Polizzi, Karen; Elowitz, Michael B; Fussenegger, Martin; Hilton, Isaac B; Leonard, Joshua N; Bintu, Lacramioara; Galloway, Kate E; Deans, Tara L.
Afiliação
  • Cabrera A; Department of Bioengineering, Rice University, Houston, TX 77005, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Edelstein HI; Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA; The Eli and Edythe Broad CIRM Center, Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Glykofrydis F; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033-9080, USA.
  • Love KS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Palacios S; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Tycko J; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
  • Zhang M; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Champaign, Urbana, IL 61801, USA.
  • Lensch S; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
  • Shields CE; Wallace H. Coulter Department of Biomedical Engineering, Emory University, Atlanta, GA 30322, USA.
  • Livingston M; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112, USA.
  • Weiss R; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridg
  • Zhao H; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Champaign, Urbana, IL 61801, USA.
  • Haynes KA; Wallace H. Coulter Department of Biomedical Engineering, Emory University, Atlanta, GA 30322, USA.
  • Morsut L; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033-9080, USA.
  • Chen YY; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA; Parker Institute for Cancer Immunotherapy Center
  • Khalil AS; Biological Design Center and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Wong WW; Biological Design Center and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
  • Collins JJ; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA 90033-9080, USA; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston,
  • Rosser SJ; School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
  • Polizzi K; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, UK; Imperial College Centre for Synthetic Biology, South Kensington Campus, London, UK.
  • Elowitz MB; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.
  • Fussenegger M; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, Basel 4058, Switzerland; Faculty of Science, University of Basel, Mattenstrasse 26, Basel 4058, Switzerland.
  • Hilton IB; Department of Bioengineering, Rice University, Houston, TX 77005, USA.
  • Leonard JN; Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA; The Eli and Edythe Broad CIRM Center, Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Bintu L; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
  • Galloway KE; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Deans TL; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: tara.deans@utah.edu.
Cell Syst ; 13(12): 950-973, 2022 12 21.
Article em En | MEDLINE | ID: mdl-36549273
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / Redes Reguladoras de Genes Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / Redes Reguladoras de Genes Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article