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Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Siena, Emilio; Schiavetti, Francesca; Borgogni, Erica; Taccone, Marianna; Faenzi, Elisa; Brazzoli, Michela; Aprea, Susanna; Bardelli, Monia; Volpini, Gianfranco; Buricchi, Francesca; Sammicheli, Chiara; Tavarini, Simona; Bechtold, Viviane; Blohmke, Christoph J; Cardamone, Dario; De Intinis, Carlo; Gonzalez-Lopez, Antonio; O'Hagan, Derek T; Nuti, Sandra; Seidl, Claudia; Didierlaurent, Arnaud M; Bertholet, Sylvie; D'Oro, Ugo; Medini, Duccio; Finco, Oretta.
Afiliação
  • Siena E; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: emilio.x.siena@gsk.com.
  • Schiavetti F; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: francesca.x.schiavetti@gsk.com.
  • Borgogni E; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: erica.x.borgogni@gsk.com.
  • Taccone M; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: marianna.x.taccone@gsk.com.
  • Faenzi E; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: elisa.x.faenzi@gsk.com.
  • Brazzoli M; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: michela.x.brazzoli@gsk.com.
  • Aprea S; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: susanna.x.aprea@gsk.com.
  • Bardelli M; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: monia.x.bardelli@gsk.com.
  • Volpini G; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: gifox1960@yahoo.it.
  • Buricchi F; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: francesca.x.buricchi@gsk.com.
  • Sammicheli C; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: chiara.x.sammicheli@gsk.com.
  • Tavarini S; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: simona.x.tavarini@gsk.com.
  • Bechtold V; GSK, Rue de l'Institut 89, 1330 Rixensart, Belgium. Electronic address: viviane.x.bechtold@gsk.com.
  • Blohmke CJ; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: christoph.j.blohmke@gsk.com.
  • Cardamone D; Toscana Life Sciences Foundation, Siena, Italy. Electronic address: d.cardamone@toscanalifesciences.org.
  • De Intinis C; GSK, Via Fiorentina 1, 53100 Siena, Italy; University of Turin, Via Verdi 8, 10124 Torino, Italy. Electronic address: carlo.deintinis@gmail.com.
  • Gonzalez-Lopez A; GSK, 14200 Shady Grove Rd, Rockville MD, USA. Electronic address: antoniogonzalezlopez17@gmail.com.
  • O'Hagan DT; University of Turin, Via Verdi 8, 10124 Torino, Italy. Electronic address: hagan@gsk.com.
  • Nuti S; GSK, 14200 Shady Grove Rd, Rockville MD, USA. Electronic address: sandra.x.nuti@gsk.com.
  • Seidl C; GSK, 14200 Shady Grove Rd, Rockville MD, USA. Electronic address: claudia.x.seidl@gsk.com.
  • Didierlaurent AM; GSK, Rue de l'Institut 89, 1330 Rixensart, Belgium. Electronic address: arnaud.didierlaurent@unige.ch.
  • Bertholet S; GSK, 14200 Shady Grove Rd, Rockville MD, USA. Electronic address: sylvie.c.bertholet-girardin@gsk.com.
  • D'Oro U; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: ugo.x.doro@gsk.com.
  • Medini D; Toscana Life Sciences Foundation, Siena, Italy. Electronic address: d.medini@toscanalifesciences.org.
  • Finco O; GSK, Via Fiorentina 1, 53100 Siena, Italy. Electronic address: oretta.x.finco@gsk.com.
Vaccine ; 41(3): 724-734, 2023 01 16.
Article em En | MEDLINE | ID: mdl-36564274
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Meningocócicas / Hidróxido de Alumínio Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Meningocócicas / Hidróxido de Alumínio Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article