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Inhibition of GPR39 restores defects in endothelial cell-mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis.
Meda Venkata, Sai Pranathi; Li, Hainan; Xu, Liping; Koh, Jia Yi; Nguyen, Huong; Minjares, Morgan; Li, Chunying; Kowluru, Anjaneyulu; Milligan, Graeme; Wang, Jie-Mei.
Afiliação
  • Meda Venkata SP; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Li H; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Xu L; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Koh JY; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Nguyen H; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Minjares M; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Li C; Center of Molecular and Translational Medicine and the Institute of Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
  • Kowluru A; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201.
  • Milligan G; John D. Dingell Department of Veterans Affairs Medical Center, Detroit, MI 48201.
  • Wang JM; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
Proc Natl Acad Sci U S A ; 120(1): e2208541120, 2023 01 03.
Article em En | MEDLINE | ID: mdl-36574661
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Hiperglicemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Hiperglicemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article