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Miglustat, a glucosylceramide synthase inhibitor, mitigates liver fibrosis through TGF-ß/Smad pathway suppression in hepatic stellate cells.
Iwanaga, Terunao; Chiba, Tetsuhiro; Nakamura, Masato; Kaneko, Tatsuya; Ao, Junjie; Qiang, Na; Ma, Yaojia; Zhang, Jiaqi; Kogure, Tadayoshi; Yumita, Sae; Ishino, Takamasa; Ogawa, Keita; Kan, Motoyasu; Nakagawa, Miyuki; Fujiwara, Kisako; Fujita, Naoto; Sakuma, Takafumi; Kanzaki, Hiroaki; Koroki, Keisuke; Kusakabe, Yuko; Inoue, Masanori; Kobayashi, Kazufumi; Kanogawa, Naoya; Kiyono, Soichiro; Kondo, Takayuki; Nakagawa, Ryo; Ogasawara, Sadahisa; Nakamoto, Shingo; Muroyama, Ryosuke; Kato, Jun; Kanda, Tatsuo; Maruyama, Hitoshi; Mimura, Naoya; Honda, Takuya; Murayama, Toshihiko; Nakamura, Hiroyuki; Kato, Naoya.
Afiliação
  • Iwanaga T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Chiba T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan. Electronic address: chibatet@chiba-u.jp.
  • Nakamura M; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kaneko T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Ao J; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Qiang N; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Ma Y; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Zhang J; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kogure T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Yumita S; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Ishino T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Ogawa K; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kan M; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakagawa M; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Fujiwara K; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Fujita N; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Sakuma T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kanzaki H; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Koroki K; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kusakabe Y; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Inoue M; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kobayashi K; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kanogawa N; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kiyono S; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kondo T; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakagawa R; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Ogasawara S; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakamoto S; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Muroyama R; Department of Molecular Virology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kato J; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Kanda T; Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
  • Maruyama H; Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
  • Mimura N; Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan.
  • Honda T; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Murayama T; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Nakamura H; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Kato N; Department of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Biochem Biophys Res Commun ; 642: 192-200, 2023 01 29.
Article em En | MEDLINE | ID: mdl-36586187
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Fator de Crescimento Transformador beta1 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Fator de Crescimento Transformador beta1 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article