Seven new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla.
Fitoterapia
; 165: 105421, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36587748
ABSTRACT
Two rare flavonoid-2-(2-phenylethyl)chromones and five new dimeric 2-(2-phenylethyl)chromones were isolated from ethanol extract of agarwood of Aquilaria walla by LC-MS-guided fractionation procedure. Their structures were established based on extensive spectroscopic methods including HRESIMS, 1D and 2D NMR, as well as by comparison with the literature. Compound 1 showed cytotoxic activity against five human cancer cell lines with IC50 values ranging from 13.40 to 28.96 µM with cisplatin as the positive control.
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Base de dados:
MEDLINE
Assunto principal:
Cromonas
/
Thymelaeaceae
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article