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Seven new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla.
Chen, Leyao; Chen, Huiqin; Cai, Caihong; Yuan, Jingzhe; Gai, Cuijuan; Liu, Shoubai; Mei, Wenli; Dai, Haofu.
Afiliação
  • Chen L; School of Forestry, Hainan University, Haikou 570228, PR China; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.
  • Chen H; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.
  • Cai C; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.
  • Yuan J; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.
  • Gai C; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.
  • Liu S; School of Forestry, Hainan University, Haikou 570228, PR China.
  • Mei W; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China. Electronic address: meiwenli@itbb.org.cn.
  • Dai H; Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China. Electronic address: daihaofu@itbb.org.cn.
Fitoterapia ; 165: 105421, 2023 Mar.
Article em En | MEDLINE | ID: mdl-36587748
ABSTRACT
Two rare flavonoid-2-(2-phenylethyl)chromones and five new dimeric 2-(2-phenylethyl)chromones were isolated from ethanol extract of agarwood of Aquilaria walla by LC-MS-guided fractionation procedure. Their structures were established based on extensive spectroscopic methods including HRESIMS, 1D and 2D NMR, as well as by comparison with the literature. Compound 1 showed cytotoxic activity against five human cancer cell lines with IC50 values ranging from 13.40 to 28.96 µM with cisplatin as the positive control.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromonas / Thymelaeaceae Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromonas / Thymelaeaceae Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article