Synthesis of selenophene-based chalcone analogs and assessment of their biological activity as anticancer agents.

Chen, Ya-Chen; Li, Cai-Wei; Chen, Jih-Jung; Shih, Tzenge-Lien

Chen, Ya-Chen; Li, Cai-Wei; Chen, Jih-Jung; Shih, Tzenge-Lien.

Afiliação

Chen YC; Department of Chemistry, Tamkang University, New Taipei City, Taiwan.
Li CW; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chen JJ; Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Shih TL; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.

Arch Pharm (Weinheim) ; 356(4): e2200486, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36587972

Assuntos

Antineoplásicos; Chalcona; Chalconas; Selênio; Humanos; Chalconas/farmacologia; Selênio/farmacologia; Relação Estrutura-Atividade; Proliferação de Células; Antineoplásicos/farmacologia; Apoptose; Ensaios de Seleção de Medicamentos Antitumorais; Linhagem Celular Tumoral; Estrutura Molecular

Palavras-chave

anticancer; chalcone; human colorectal adenocarcinoma cell; selenophene

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Selênio / Chalcona / Chalconas / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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