A Cell-Permeant Nanobody-Based Degrader That Induces Fetal Hemoglobin.

Shen, Fangfang; Zheng, Ge; Setegne, Mekedlawit; Tenglin, Karin; Izadi, Manizheh; Xie, Henry; Zhai, Liting; Orkin, Stuart H; Dassama, Laura M K.

Afiliação

Shen F; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, California 94305, United States.
Zheng G; Dana Farber Boston Children's Cancer and Blood Disorders Center and Howard Hughes Medical Institute, Boston, Massachusetts 02215, United States.
Setegne M; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, United States.
Tenglin K; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, California 94305, United States.
Izadi M; Dana Farber Boston Children's Cancer and Blood Disorders Center and Howard Hughes Medical Institute, Boston, Massachusetts 02215, United States.
Xie H; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, United States.
Zhai L; Dana Farber Boston Children's Cancer and Blood Disorders Center and Howard Hughes Medical Institute, Boston, Massachusetts 02215, United States.
Orkin SH; Dana Farber Boston Children's Cancer and Blood Disorders Center and Howard Hughes Medical Institute, Boston, Massachusetts 02215, United States.
Dassama LMK; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, United States.

ACS Cent Sci ; 8(12): 1695-1703, 2022 Dec 28.

Article em En | MEDLINE | ID: mdl-36589886

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article