Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene.

Ortega, Mireia; De Toma, Ilario; Fernández-Blanco, Álvaro; Calderón, Anna; Barahona, Lucía; Trullàs, Ramón; Sabidó, Eduard; Dierssen, Mara.

Afiliação

Ortega M; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
De Toma I; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Fernández-Blanco Á; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Calderón A; Instituto de Investigaciones Biomédicas de Barcelona, IIBB/CSIC y Centro de Investigación Biomédica en Red, Barcelona, Spain.
Barahona L; Instituto de Investigaciones Biomédicas de Barcelona, IIBB/CSIC y Centro de Investigación Biomédica en Red, Barcelona, Spain.
Trullàs R; Instituto de Investigaciones Biomédicas de Barcelona, IIBB/CSIC y Centro de Investigación Biomédica en Red, Barcelona, Spain.
Sabidó E; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Dierssen M; Department of Experimental Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.

Front Mol Neurosci ; 15: 1015220, 2022.

Article em En | MEDLINE | ID: mdl-36590914