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Drug Safety Profiles of Geriatric Patients Referred to Consultation Psychiatry in the Emergency Department-A Retrospective Cohort Study.
Schulze Westhoff, Martin; Schröder, Sebastian; Heck, Johannes; Brod, Torben; Winkelmann, Marcel; Bleich, Stefan; Frieling, Helge; Jahn, Kirsten; Wedegärtner, Felix; Groh, Adrian.
Afiliação
  • Schulze Westhoff M; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Schröder S; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Heck J; Institute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
  • Brod T; Emergency Department, Hannover Medical School, Hannover, Germany.
  • Winkelmann M; Trauma Department, Hannover Medical School, Hannover, Germany.
  • Bleich S; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Frieling H; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Jahn K; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Wedegärtner F; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
  • Groh A; Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
J Geriatr Psychiatry Neurol ; 36(5): 407-416, 2023 09.
Article em En | MEDLINE | ID: mdl-36592403
OBJECTIVE: Geriatric patients account for a significant proportion of the collective treated by psychiatric consultation service in hospitals. In the Emergency Department (ED), psychotropic drugs are frequently recommended, notwithstanding their extensive side-effect profiles. This study sought to investigate medication safety of geriatric patients referred to psychiatric consultation service in the ED. METHODS: Medication lists of 60 patients from the general internal medicine and trauma surgery EDs referred to psychiatric consultation service were analyzed. Utilizing PRISCUS list and Fit fOR The Aged (FORTA) classification, prescriptions of potentially inappropriate medications (PIMs) were assessed. RESULTS: 84 drugs were newly prescribed following psychiatric consultations. The total number of drugs per patient was 5.4 ± 4.2 before psychiatric consultation and 6.5 ± 4.2 thereafter (p < .001). 22.6 % of the newly recommended drugs were PIMs according to the PRISCUS list, while 54.8 % were designated as therapeutic alternatives to PIMs. 54.8 % and 20.2 % of the newly recommended drugs were FORTA category C and D drugs, respectively. An average of 1.2 ± 1.7 drug-drug interactions (DDIs) existed before psychiatric consultation and 1.3 ± 1.9 DDIs thereafter (p = .08). CONCLUSION: The majority of newly recommended drugs by psychiatric consultation service in the ED were designated as suitable therapeutic alternatives to PIMs according to the PRISCUS list, but had comparatively unfavorable ratings according to the FORTA classification, demonstrating discrepancies between these two PIM classification systems. Physicians delivering psychiatric consultation services in the ED should not solely rely on one PIM classification system.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psiquiatria / Prescrição Inadequada Tipo de estudo: Etiology_studies / Observational_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psiquiatria / Prescrição Inadequada Tipo de estudo: Etiology_studies / Observational_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article