Repurposing Carbamazepine To Treat Gonococcal Infection in Women: Oral Delivery for Control of Epilepsy Generates Therapeutically Effective Levels in Vaginal Secretions.

Shewell, Lucy K; Day, Christopher J; De Bisscop, Xavier; Edwards, Jennifer L; Jennings, Michael P

Shewell, Lucy K; Day, Christopher J; De Bisscop, Xavier; Edwards, Jennifer L; Jennings, Michael P.

Afiliação

Shewell LK; Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.
Day CJ; Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.
De Bisscop X; Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.
Edwards JL; The Center for Microbial Pathogenesis, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Jennings MP; The Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA.

Antimicrob Agents Chemother ; 67(1): e0096822, 2023 01 24.

Article em En | MEDLINE | ID: mdl-36602335

Assuntos

Epilepsia; Gonorreia; Humanos; Feminino; Reposicionamento de Medicamentos; Gonorreia/tratamento farmacológico; Neisseria gonorrhoeae; Carbamazepina/uso terapêutico; Carbamazepina/farmacologia

Palavras-chave

Neisseria gonorrhoeae; antimicrobial agents; carbamazepine; drug repurposing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gonorreia / Epilepsia Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gonorreia / Epilepsia Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article