Current concepts and advances in dermatomyositis: a dermatological perspective.
Clin Exp Rheumatol
; 41(2): 359-369, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36622138
Dermatomyositis (DM) is an autoimmune disorder in which clinically amyopathic DM, characterised by hallmark cutaneous findings in the absence of clinical weakness, represents 20% of patients. This review will highlight current concepts and recent advances made in DM from a dermatological perspective, with a discussion of skin-predominant DM and its distinct challenges regarding diagnosis and management as well as their implications in clinical trials. An update will be presented with respect to classification criteria, pathogenesis in cutaneous DM, myositis-specific autoantibodies and their associations with cutaneous findings, skin-specific outcome measures and new therapeutics with their efficacy in skin disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Dermatomiosite
/
Miosite
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article