Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells.

Matthews, Joseph J; Turner, Mark D; Santos, Livia; Elliott-Sale, Kirsty J; Sale, Craig

Matthews, Joseph J; Turner, Mark D; Santos, Livia; Elliott-Sale, Kirsty J; Sale, Craig.

Afiliação

Matthews JJ; Sport, Health and Performance Research Centre, Musculoskeletal Physiology Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
Turner MD; Department of Sport and Exercise, Centre for Life and Sport Sciences (CLaSS), Birmingham City University, Birmingham, UK.
Santos L; Centre for Diabetes, Chronic Diseases & Ageing, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
Elliott-Sale KJ; Sport, Health and Performance Research Centre, Musculoskeletal Physiology Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
Sale C; Sport, Health and Performance Research Centre, Musculoskeletal Physiology Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, UK.

Amino Acids ; 55(3): 413-420, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36637533

Assuntos

Carnosina; Diabetes Mellitus Tipo 2; Resistência à Insulina; Humanos; Insulina/metabolismo; Carnosina/farmacologia; Carnosina/metabolismo; Aldeído Pirúvico/farmacologia; Aldeído Pirúvico/metabolismo; Óxido de Magnésio/metabolismo; Fibras Musculares Esqueléticas/metabolismo; Músculo Esquelético/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Glucose/metabolismo; beta-Alanina/metabolismo

Palavras-chave

Diabetes; Glycaemia; Metabolism; Prediabetes; Therapeutics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Carnosina / Diabetes Mellitus Tipo 2 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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