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A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease.
Jones, Megan E; Büchler, Johanna; Dufor, Tom; Palomer, Ernest; Teo, Samuel; Martin-Flores, Nuria; Boroviak, Katharina; Metzakopian, Emmanouil; Gibb, Alasdair; Salinas, Patricia C.
Afiliação
  • Jones ME; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Büchler J; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Dufor T; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Palomer E; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Teo S; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Martin-Flores N; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
  • Boroviak K; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Metzakopian E; UK Dementia Research Institute, Department of Clinical Neuroscience, University of Cambridge, Cambridge CB2 0AH, UK.
  • Gibb A; Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.
  • Salinas PC; Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
Sci Adv ; 9(2): eabo7421, 2023 01 13.
Article em En | MEDLINE | ID: mdl-36638182
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Proteína-6 Relacionada a Receptor de Lipoproteína de Baixa Densidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer / Proteína-6 Relacionada a Receptor de Lipoproteína de Baixa Densidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article