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GDF15 neutralization restores muscle function and physical performance in a mouse model of cancer cachexia.
Kim-Muller, Ja Young; Song, LouJin; LaCarubba Paulhus, Brianna; Pashos, Evanthia; Li, Xiangping; Rinaldi, Anthony; Joaquim, Stephanie; Stansfield, John C; Zhang, Jiangwei; Robertson, Andrew; Pang, Jincheng; Opsahl, Alan; Boucher, Magalie; Breen, Danna; Hales, Katherine; Sheikh, Abdul; Wu, Zhidan; Zhang, Bei B.
Afiliação
  • Kim-Muller JY; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Song L; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • LaCarubba Paulhus B; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Pashos E; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Li X; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Rinaldi A; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Joaquim S; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Stansfield JC; Biostatistics, Early Clinical Development, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Zhang J; Drug Safety Research & Development, Pfizer Worldwide Research, Development & Medical, 10777 Science Center Dr., San Diego, CA, USA.
  • Robertson A; Drug Safety Research & Development, Pfizer Worldwide Research, Development & Medical, 445 Eastern Point Rd., Groton, CT, USA.
  • Pang J; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Opsahl A; Drug Safety Research & Development, Pfizer Worldwide Research, Development & Medical, 445 Eastern Point Rd., Groton, CT, USA.
  • Boucher M; Drug Safety Research & Development, Pfizer Worldwide Research, Development & Medical, 445 Eastern Point Rd., Groton, CT, USA.
  • Breen D; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Hales K; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Sheikh A; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Wu Z; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA.
  • Zhang BB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development & Medical, 1 Portland St., Cambridge, MA, USA. Electronic address: beibetty.zhang@pfizer.com.
Cell Rep ; 42(1): 111947, 2023 01 31.
Article em En | MEDLINE | ID: mdl-36640326
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caquexia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caquexia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article