A single- and multiple-dose study to characterize the pharmacokinetics, safety, and tolerability of ceftolozane/tazobactam in healthy Chinese participants.

Liu, Na; Wang, Xiaohong; Zhu, Jixiang; Basu, Sumit; Wei, Yudong; Yan, Bei; Wang, Hui; Colon-Gonzalez, Francheska; Feng, Hwa-Ping; Sun, Fang; Li, Haiyan; Zang, Yanqiao

Liu, Na; Wang, Xiaohong; Zhu, Jixiang; Basu, Sumit; Wei, Yudong; Yan, Bei; Wang, Hui; Colon-Gonzalez, Francheska; Feng, Hwa-Ping; Sun, Fang; Li, Haiyan; Zang, Yanqiao.

Afiliação

Liu N; Beijing Haidian Hospital (Haidian Section of Peking University Third Hospital), China.
Wang X; Peking University Third Hospital, Beijing, China.
Zhu J; Peking University Third Hospital, Beijing, China.
Basu S; Merck & Co., Inc., Rahway, NJ, USA.
Wei Y; Peking University Third Hospital, Beijing, China.
Yan B; MSD, Beijing, China.
Wang H; MSD, Beijing, China.
Colon-Gonzalez F; Merck & Co., Inc., Rahway, NJ, USA.
Feng HP; Merck & Co., Inc., Rahway, NJ, USA.
Sun F; MSD, Beijing, China.
Li H; Peking University Third Hospital, Beijing, China. Electronic address: haiyanli1027@hotmail.com.
Zang Y; MSD, Beijing, China.

Int J Antimicrob Agents ; 61(3): 106717, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36640850

Assuntos

Antibacterianos; Cefalosporinas; População do Leste Asiático; Tazobactam; Humanos; Antibacterianos/administração & dosagem; Antibacterianos/farmacocinética; Cefalosporinas/administração & dosagem; Cefalosporinas/farmacocinética

Palavras-chave

Antibiotics; Asian ethnicity; Ceftolozane; Pazobactam; Pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cefalosporinas / Tazobactam / População do Leste Asiático / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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