Experimental analysis of bladder cancer-associated mutations in EP300 identifies EP300-R1627W as a driver mutation.

Luo, Mayao; Zhang, Yifan; Xu, Zhuofan; Lv, Shidong; Wei, Qiang; Dang, Qiang

Luo, Mayao; Zhang, Yifan; Xu, Zhuofan; Lv, Shidong; Wei, Qiang; Dang, Qiang.

Afiliação

Luo M; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhang Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xu Z; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Lv S; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wei Q; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. qwei@smu.edu.cn.
Dang Q; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. dangqiang0128@163.com.

Mol Med ; 29(1): 7, 2023 01 16.

Article em En | MEDLINE | ID: mdl-36647005

Assuntos

Neoplasias da Bexiga Urinária; Humanos; Neoplasias da Bexiga Urinária/genética; Neoplasias da Bexiga Urinária/metabolismo; Mutação; Histonas; Ciclo Celular; Proteína p300 Associada a E1A/genética; Proteína p300 Associada a E1A/metabolismo

Palavras-chave

Bladder cancer; Driver mutation; EP300; Missense mutation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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