[The Relationship Between Oral Microbiota and Chronic Obstructive Pulmonary Disease].
Sichuan Da Xue Xue Bao Yi Xue Ban
; 54(1): 54-60, 2023 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-36647643
ABSTRACT
Oral microbiota have a complex impact on the host's health and disease states. It has been found that the composition of lung flora bears a striking resemblance to the composition of oral flora. Moreover, oral pathogenic bacteria have been detected in the sputum and bronchoalveolar lavage fluid of patients with chronic obstructive pulmonary disease (COPD), suggesting that oral microbiota play an important role in the pathogenesis and development of COPD. Findings from lots of studies have shown that oral microbiota may participate in the pathogenesis and development of COPD through non-specific immune response, specific immune response, and the activities of protein hydrolase. Herein, we mainly summarized the available evidence on the relationship between oral microbiota and COPD. By examining the relationship between the two, we elaborated on the application of oral microbiota in the diagnosis and prevention of COPD, discussed possible directions for future research, and provided references for developing new therapeutic approaches.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença Pulmonar Obstrutiva Crônica
/
Microbiota
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article