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BTG1 mutation yields supercompetitive B cells primed for malignant transformation.
Mlynarczyk, Coraline; Teater, Matt; Pae, Juhee; Chin, Christopher R; Wang, Ling; Arulraj, Theinmozhi; Barisic, Darko; Papin, Antonin; Hoehn, Kenneth B; Kots, Ekaterina; Ersching, Jonatan; Bandyopadhyay, Arnab; Barin, Ersilia; Poh, Hui Xian; Evans, Chiara M; Chadburn, Amy; Chen, Zhengming; Shen, Hao; Isles, Hannah M; Pelzer, Benedikt; Tsialta, Ioanna; Doane, Ashley S; Geng, Huimin; Rehman, Muhammad Hassan; Melnick, Jonah; Morgan, Wyatt; Nguyen, Diu T T; Elemento, Olivier; Kharas, Michael G; Jaffrey, Samie R; Scott, David W; Khelashvili, George; Meyer-Hermann, Michael; Victora, Gabriel D; Melnick, Ari.
Afiliação
  • Mlynarczyk C; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Teater M; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Pae J; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
  • Chin CR; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Wang L; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Arulraj T; Tri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA.
  • Barisic D; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Papin A; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Hoehn KB; Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Kots E; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Ersching J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Bandyopadhyay A; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
  • Barin E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Poh HX; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.
  • Evans CM; Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Chadburn A; Department of Pharmacology and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Chen Z; Department of Pharmacology and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Shen H; Molecular Pharmacology Program and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Isles HM; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
  • Pelzer B; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Tsialta I; Division of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
  • Doane AS; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Geng H; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Rehman MH; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Melnick J; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Morgan W; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Nguyen DTT; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Elemento O; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.
  • Kharas MG; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Jaffrey SR; Weill Cornell Medicine-Qatar, Doha, Qatar.
  • Scott DW; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Khelashvili G; Division of Hematology and Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Meyer-Hermann M; Molecular Pharmacology Program and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Victora GD; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Melnick A; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Science ; 379(6629): eabj7412, 2023 01 20.
Article em En | MEDLINE | ID: mdl-36656933
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Transformação Celular Neoplásica / Linfoma Difuso de Grandes Células B / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Transformação Celular Neoplásica / Linfoma Difuso de Grandes Células B / Proteínas de Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article