Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection.

Zambalde, Érika Pereira; Dias, Thomaz Luscher; Maktura, Grazielle Celeste; Amorim, Mariene R; Brenha, Bianca; Santos, Luana Nunes; Buscaratti, Lucas; Elston, João Gabriel de Angeli; Mancini, Mariana Camargo Silva; Pavan, Isadora Carolina Betim; Toledo-Teixeira, Daniel A; Bispo-Dos-Santos, Karina; Parise, Pierina L; Morelli, Ana Paula; Silva, Luiz Guilherme Salvino da; Castro, Ícaro Maia Santos de; Saccon, Tatiana D; Mori, Marcelo A; Granja, Fabiana; Nakaya, Helder I; Proenca-Modena, Jose Luiz; Marques-Souza, Henrique; Simabuco, Fernando Moreira

Zambalde, Érika Pereira; Dias, Thomaz Luscher; Maktura, Grazielle Celeste; Amorim, Mariene R; Brenha, Bianca; Santos, Luana Nunes; Buscaratti, Lucas; Elston, João Gabriel de Angeli; Mancini, Mariana Camargo Silva; Pavan, Isadora Carolina Betim; Toledo-Teixeira, Daniel A; Bispo-Dos-Santos, Karina; Parise, Pierina L; Morelli, Ana Paula; Silva, Luiz Guilherme Salvino da; Castro, Ícaro Maia Santos de; Saccon, Tatiana D; Mori, Marcelo A; Granja, Fabiana; Nakaya, Helder I; Proenca-Modena, Jose Luiz; Marques-Souza, Henrique; Simabuco, Fernando Moreira.

Afiliação

Zambalde ÉP; Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira 13484-350, SP, Brazil.
Dias TL; Computational Systems Biology Lab (CSBL), Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
Maktura GC; Laboratório de Genética Bioquímica, Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, MG, Brazil.
Amorim MR; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Brenha B; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Santos LN; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Buscaratti L; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Elston JGA; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Mancini MCS; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas 13083-872, SP, Brazil.
Pavan ICB; Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira 13484-350, SP, Brazil.
Toledo-Teixeira DA; Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira 13484-350, SP, Brazil.
Bispo-Dos-Santos K; Laboratory of Signaling Mechanisms (LMS), School of Pharmaceutical Sciences (FCF), University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Parise PL; Laboratory of Emerging Viruses (LEVE), Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Morelli AP; Laboratory of Emerging Viruses (LEVE), Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Silva LGSD; Laboratory of Emerging Viruses (LEVE), Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Castro ÍMS; Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira 13484-350, SP, Brazil.
Saccon TD; Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira 13484-350, SP, Brazil.
Mori MA; Computational Systems Biology Lab (CSBL), Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
Granja F; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Nakaya HI; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Proenca-Modena JL; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Marques-Souza H; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Simabuco FM; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, University of Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.