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BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8+ T cells.
Romine, Kyle A; MacPherson, Kevin; Cho, Hyun-Jun; Kosaka, Yoko; Flynn, Patrick A; Byrd, Kaelan H; Coy, Jesse L; Newman, Matthew T; Pandita, Ravina; Loo, Christopher P; Scott, Jaime; Adey, Andrew C; Lind, Evan F.
Afiliação
  • Romine KA; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA.
  • MacPherson K; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Cho HJ; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Kosaka Y; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Flynn PA; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Byrd KH; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Coy JL; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Newman MT; School of Medicine, Oregon Health & Science University, Portland, OR, USA.
  • Pandita R; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA.
  • Loo CP; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Scott J; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Adey AC; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Lind EF; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Leukemia ; 37(3): 580-592, 2023 03.
Article em En | MEDLINE | ID: mdl-36681742
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Linfócitos T CD8-Positivos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Linfócitos T CD8-Positivos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article