Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma.

Thng, Dexter Kai Hao; Toh, Tan Boon; Pigini, Paolo; Hooi, Lissa; Dan, Yock Young; Chow, Pierce Kah-Hoe; Bonney, Glenn Kunnath; Rashid, Masturah Bte Mohd Abdul; Guccione, Ernesto; Wee, Dave Keng Boon; Chow, Edward Kai-Hua

Thng, Dexter Kai Hao; Toh, Tan Boon; Pigini, Paolo; Hooi, Lissa; Dan, Yock Young; Chow, Pierce Kah-Hoe; Bonney, Glenn Kunnath; Rashid, Masturah Bte Mohd Abdul; Guccione, Ernesto; Wee, Dave Keng Boon; Chow, Edward Kai-Hua.

Afiliação

Thng DKH; Cancer Science Institute of Singapore, National University of Singapore Singapore Singapore.
Toh TB; The N.1 Institute for Health, National University of Singapore Singapore Singapore.
Pigini P; The Institute for Digital Medicine (WisDM), Yong Loo Lin School of Medicine, National University of Singapore Singapore.
Hooi L; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (ASTAR) Singapore Singapore.
Dan YY; Cancer Science Institute of Singapore, National University of Singapore Singapore Singapore.
Chow PK; NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
Bonney GK; Cancer Science Institute of Singapore, National University of Singapore Singapore Singapore.
Rashid MBMA; Division of Gastroenterology and Hepatology National University Health System Singapore Singapore.
Guccione E; Department of Medicine, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
Wee DKB; Division of Surgical Oncology National Cancer Centre Singapore Singapore Singapore.
Chow EK; Department of Hepato-Pancreato-Biliary and Transplant Surgery Singapore General Hospital Singapore Singapore.