Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling.

Müller, Lisa; Keil, René; Hatzfeld, Mechthild

Müller, Lisa; Keil, René; Hatzfeld, Mechthild.

Afiliação

Müller L; Charles Tanford Protein Research Center, Martin Luther University Halle, Institute of Molecular Medicine, Department for Pathobiochemistry, Kurt-Mothes-Str. 3A, 06120 Halle, Germany. Electronic address: lisa.mueller@uk-halle.de.
Keil R; Charles Tanford Protein Research Center, Martin Luther University Halle, Institute of Molecular Medicine, Department for Pathobiochemistry, Kurt-Mothes-Str. 3A, 06120 Halle, Germany.
Hatzfeld M; Charles Tanford Protein Research Center, Martin Luther University Halle, Institute of Molecular Medicine, Department for Pathobiochemistry, Kurt-Mothes-Str. 3A, 06120 Halle, Germany. Electronic address: mechthild.hatzfeld@medizin.uni-halle.de.

Cell Rep ; 42(1): 112031, 2023 01 31.

Article em En | MEDLINE | ID: mdl-36689330

Assuntos

Placofilinas; Proteína do Retinoblastoma; Animais; Camundongos; Divisão Celular; Citoplasma/metabolismo; Fator de Transcrição E2F1/metabolismo; Receptores ErbB/metabolismo; Fosforilação; Placofilinas/genética; Placofilinas/metabolismo; Proteína do Retinoblastoma/metabolismo; Fase S; Transdução de Sinais

Palavras-chave

CDKN1A/p21; CP: Cell biology; CP: Molecular biology; EGF signaling; G1 phase; RB; RSK1; RUNX3; cell cycle; plakophilin 3; proliferation; retinoblastoma protein

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína do Retinoblastoma / Placofilinas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google