Updates in neuroendocrine neoplasms: From mechanisms to the clinic.
Ann Endocrinol (Paris)
; 84(2): 291-297, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-36690074
Scientific advances constantly improve our understanding of the mechanisms underlying tumorigenesis, allowing us now to analyze cancer in a more precise manner and to identify at an earlier stage the tumors that have greater risk of aggressive behavior. Understanding neuroendocrine neoplasms at molecular level has enabled increasingly targeted treatments, with safety and efficacy validated in large randomized trials. Moreover, the first studies of targeted therapies after molecular profiling of neuroendocrine neoplasms have shown encouraging results, allowing us to foresee ever more personalized medical treatments in the future. This literature review aims to summarize recent advances in the study of neuroendocrine neoplasms and to show how identification of new mechanisms underlying tumorigenesis can be of benefit in clinical practice.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paraganglioma
/
Tumores Neuroendócrinos
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Neoplasias das Glândulas Suprarrenais
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article