Potent Dual Polymerase/Exonuclease Inhibitory Activities of Antioxidant Aminothiadiazoles Against the COVID-19 Omicron Virus: A Promising In Silico/In Vitro Repositioning Research Study.

Rabie, Amgad M; Eltayb, Wafa A

Rabie, Amgad M; Eltayb, Wafa A.

Afiliação

Rabie AM; Dr. Amgad Rabie's Research Lab. for Drug Discovery (DARLD), Mansoura City, Mansoura, 35511, Dakahlia Governorate, Egypt. amgadpharmacist1@yahoo.com.
Eltayb WA; Head of Drug Discovery & Clinical Research Department, Dikernis General Hospital (DGH), Magliss El-Madina Street, Dikernis City, Dikernis, 35744, Dakahlia Governorate, Egypt. amgadpharmacist1@yahoo.com.

Mol Biotechnol ; 2023 Jan 24.

Article em En | MEDLINE | ID: mdl-36690820

Palavras-chave

2-Amino-1,3,4-thiadiazole Derivative; Anti-COVID-19 Drug; Anti-Omicron Agent; ChloViD2022; Coronaviral-2 RNA-dependent RNA Polymerase (RdRp); SARS-CoV-2 Proofreading 3'-to-5' Exoribonuclease (ExoN)

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article