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Future directions for medicinal chemistry in the field of oligonucleotide therapeutics.
Hall, Jonathan.
Afiliação
  • Hall J; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland jonathan.hall@pharma.ethz.ch.
RNA ; 29(4): 423-433, 2023 04.
Article em En | MEDLINE | ID: mdl-36693762
In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single-stranded and double-stranded RNA drugs. In this Perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide chemistry.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Química Farmacêutica Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Química Farmacêutica Idioma: En Ano de publicação: 2023 Tipo de documento: Article